Creates a formal process for the President and U.S. Trade Representative to negotiate and enforce "trusted trade partner" agreements with foreign countries to strengthen and diversify U.S. medical supply chains. It requires definitions, sets goals (resilience, regulatory cooperation, IP protection, expanded manufacturing), and establishes consultation, congressional notice and review rules before agreements are concluded.

Requires periodic monitoring of partner compliance and gives the President options to suspend, terminate, or seek remedies if a partner fails to meet commitments; also mandates regular reports to Congress on negotiation status and partner performance.