This bill would put all fentanyl-related substances into Schedule I, the strictest drug category. It defines these substances broadly, covering any mix or compound with any amount of a fentanyl-like substance, including many chemical look‑alikes based on specific changes to fentanyl’s structure, like swapping certain rings or adding groups to parts of the molecule. It also says that any mandatory minimum prison term under a specific federal drug penalty section will not apply to these fentanyl‑related substances.

Key points:

• What changes: Classifies fentanyl-related substances as Schedule I using a wide, chemistry-based definition; removes mandatory minimums under one federal penalty section for these substances .
• Scope: Covers any material or mixture with any amount of a fentanyl-related substance, including salts and isomers, and lists several ways a substance can be “structurally related” to fentanyl.
• Short title: Federal Initiative to Guarantee Health by Targeting Fentanyl Act.