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Creates a new nonrefundable translational research tax credit equal to 25% of qualifying expenses for translational research on neurodegenerative diseases and psychiatric conditions. The credit is subject to annual national caps, can be transferred by certain tax-exempt entities to project partners, must be coordinated with the existing R&D credit rules, and sunsets after taxable years beginning after December 31, 2035.
The bill creates sizable, predictable tax incentives to accelerate CNS and psychiatric translational research—potentially speeding new therapies to patients and encouraging collaboration—while costing taxpayers significant revenue and creating access, administrative, and tax-planning limits for some small or non-taxable research entities.
Patients with neurodegenerative and psychiatric conditions may get faster access to new treatments because the bill prioritizes and funds translational research across the full development continuum for high-need CNS and psychiatric projects.
Scientists, hospitals, and companies developing CNS and psychiatric treatments receive a 25% tax credit on qualifying translational research costs, reducing net R&D expenses and strengthening incentives to pursue new therapies.
Researchers and institutions benefit from predictable multi-year federal support because the bill sets large aggregate annual caps ($1B–$2B) through 2031, aiding planning for multi-year translational projects.
All American taxpayers face reduced federal revenue because the program forgoes $1B–$2B annually, which could increase deficits or pressure other spending or taxes.
Startups and small nonprofits without tax liability may receive little direct benefit because the credit is nonrefundable unless they can transfer credits to partners, limiting support for early-stage innovators.
Scientists, small research entities, and nonprofits may face delays and extra administrative burden because complex allocation and transfer rules, Treasury regulations, and application processes could slow access to credits.
Introduced March 11, 2025 by Michael Thompson · Last progress March 11, 2025