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Federal Regulations

How Congress's laws become real-world rules. Browse regulatory dockets from Regulations.gov — tracking rulemaking activity, public comment periods, and the agencies turning legislation into policy.

Dockets
3,873
Regulations.gov

Showing 30 of 3,873 dockets

Nonrulemaking
FDA

FDA-2026-H-2312

DAB Civil Money Penalty; Star Mart 1 LLC d/b/a Star Mart 1; CLOSED 04/09/2026

1 docNo comments
Nonrulemaking
FDA
Open for Comments

FDA-2025-D-2275

M4Q(R2) The Common Technical Document for the Registration of Pharmaceuticals for Human Use: Quality; International Council for Harmonisation; Draft Guidance for Industry; Availability

2 docs18 comments
Comments due Mar 24, 2026
Nonrulemaking
FDA
Open for Comments

FDA-2025-D-1797

E21 Inclusion of Pregnant and Breastfeeding Women in Clinical Trials; International Council for Harmonisation; Draft Guidance for Industry; Availability

2 docs29 comments
Comments due Sep 20, 2025
Nonrulemaking
FDA
Open for Comments

FDA-2025-D-1504

Responding to FDA Form 483 Observations at the Conclusion of a Drug CGMP Inspection: Draft Guidance for Industry; Availability

2 docs13 comments
Comments due May 9, 2026
Nonrulemaking
FDA
Open for Comments

FDA-2024-D-2754

M14 General Principles on Plan, Design, and Analysis of Pharmacoepidemiological Studies that Utilize Real-World Data for Safety Assessment of Medicines; International Council for Harmonisation; Draft Guidance for Industry; Availability

4 docs12 comments
Comments due Sep 4, 2024
Nonrulemaking
PTO

PTO-P-2025-0446

0651-0022 Deposit of Biological Materials

2 docs1 comment
Nonrulemaking
FDA
Open for Comments

FDA-2024-D-2033

Expedited Program for Serious Conditions--Accelerated Approval of Drugs and Biologics; Draft Guidance for Industry; Availability

6 docs49 comments
Comments due Apr 8, 2026
Nonrulemaking
DOT
Open for Comments

DOT-OST-1997-2706

97-7-12 Order Tentatively Selecting Carrier, Setting Final Rates and Requesting Carrier Proposals re Essential Air Service at Vernal and Cedar City, Utah

354 docs15 comments
Comments due Sep 13, 2007
Rulemaking
EPA

EPA-R08-OAR-2025-0233

CO Serious Area RACT

15 docs3 comments
Rulemaking
ACF
Open for Comments

ACF-2026-0430

Reducing Bureaucracy and Burden for Family Violence and Prevention Services

1 docNo comments
Comments due May 7, 2026
Rulemaking
ACF
Open for Comments

ACF-2026-0397

Reducing Bureaucracy and Burden for Children, Youth, and Family Programs

1 docNo comments
Comments due May 7, 2026
Nonrulemaking
FTA
Open for Comments

FTA-2024-0020

Notice of Proposed Policy Statement Regarding the Applicability of FTA’s Drug and Alcohol Testing Program to Transportation Network Companies

4 docs799 comments
Comments due Feb 14, 2025
Rulemaking
EPA

EPA-R08-OAR-2024-0622

CO Serious Area Contingency Measures

20 docs2 comments
Rulemaking
ACF
Open for Comments

ACF-2026-0133

Reducing Bureaucracy and Burden for Native American Programs

2 docsNo comments
Comments due Apr 28, 2026
Rulemaking
ACF

ACF-2026-0298

Designated Placement Requirements under Titles IV-E and IV-B for LGBTQI+ Children; Rescission

1 doc1.2K comments
Rulemaking
AMS
Open for Comments

AMS-NOP-22-0029

National Organic Program: National List of Allowed and Prohibited Substances per October 2021, October 2022, and October 2024 Recommendations (Crops and Livestock)

1 doc14 comments
Comments due May 23, 2026
Rulemaking
ACF
Open for Comments

ACF-2026-0166

Reducing Bureaucracy and Burden for Refugee Resettlement Programs

2 docsNo comments
Comments due May 27, 2026
Nonrulemaking
FDA
Open for Comments

FDA-2023-P-2852

Requests that the FDA revise existing regulations and policies to require drug and dietary supplement manufacturers to clearly label whether ingredients used in their products are animal derived or contain animal byproducts.

3 docs1.6K comments
Nonrulemaking
FDA
Open for Comments

FDA-2023-D-2925

Defining Durations of Use for Approved Medically Important Antimicrobial Drugs Fed to Food-Producing Animals; Draft Guidance for Industry; Availability

8 docs4.7K comments
Comments due Jan 6, 2024
Nonrulemaking
FAA
Open for Comments

FAA-2001-8878

Exemption/Rulemaking - American Airlines - Exemption No. 6916B

33 docsNo comments
Comments due Apr 11, 2007
Nonrulemaking
FDA
Open for Comments

FDA-2022-D-2424

Protein Efficiency Ratio (PER) Rat Bioassay Studies to Demonstrate that a New Infant Formula Supports the Quality Factor of Sufficient Biological Quality of Protein; Draft Guidance for Industry; Availability; Agency Information Collection Activities; Proposed Collection; Comment Request

4 docs7 comments
Comments due May 12, 2023
Nonrulemaking
PHMSA

PHMSA-2025-0013

Algonquin Gas Transmission, LLC - Application for Special Permit for Smartpipe Installation, Line R-1, Hartford County, Connecticut

12 docs3 comments
Nonrulemaking
PHMSA

PHMSA-2026-1354

In the Matter of Lower Huron Chemical and Supply Company

1 docNo comments
Rulemaking
AMS

AMS-SC-25-0122

Honey Packers and Importers Research, Promotion, Consumer Education and Industry Information Order: Increased Assessment Rate

1 doc55 comments
Nonrulemaking
ED
Open for Comments

ED-2026-SCC-1222

William D. Ford Federal Direct Loan Program (Direct Loan Program) Promissory Notes and related forms

3 docsNo comments
Comments due Jun 9, 2026
Rulemaking
NRC
Open for Comments

NRC-2025-1503

NRC Reviews of Reactor Designs Previously Authorized by U.S. Department of Energy or Department of War (formerly titled Streamlined Reviews of Proven Reactor Designs)

2 docs9 comments
Comments due May 5, 2026
Nonrulemaking
FDA
Open for Comments

FDA-2022-D-1862

In Vitro Permeation Test Studies for Topical Products Submitted in ANDAs; Draft Guidance for Industry; Availability

2 docs1 comment
Comments due Dec 24, 2022
Nonrulemaking
FDA
Open for Comments

FDA-2021-D-1238

Celiac Disease: Developing Drugs for Adjunctive Treatment to a Gluten-Free Diet]; Draft Guidance for Industry; Availability

2 docs25 comments
Comments due Jun 15, 2022
Nonrulemaking
NHTSA

NHTSA-2026-0034

Notice and Request for Comment; Proposal for a New United Nations Global Technical Regulation on Automated Driving Systems (ADS)

5 docs65 comments
Nonrulemaking
FDA
Open for Comments

FDA-2021-D-0368

Investigator Responsibilities--Safety Reporting for Investigational Drugs and Devices; Draft Guidance for Industry; Availability

4 docs12 comments
Comments due Nov 30, 2021
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