DeOndra Dixon INCLUDE Project Act of 2025

This bill tells the National Institutes of Health (NIH) to run a program, called the INCLUDE Project, to boost research, training, and studies about Down syndrome across a person’s whole life. It aims to speed up promising research on how the extra chromosome (trisomy 21) affects health, grow inclusive clinical trials, study conditions that often occur with Down syndrome (like Alzheimer’s and autoimmune diseases), and find better ways to diagnose, treat, and improve daily life for people with Down syndrome and their families.

The bill also tells NIH to coordinate this work across its institutes so efforts aren’t duplicated, to listen to patient advocates and other stakeholders, and to report to Congress every two years on progress and real‑world results that can help patient care.

• Who is affected: People with Down syndrome and their families; doctors and researchers; NIH
• What changes: More coordinated research and clinical trials; focus on co‑occurring conditions; better tools for diagnosis and treatment; regular progress reports
• When: Creates an ongoing NIH program with reports due every two years