Creates a new NIH program called the INCLUDE Project to support research, training, and investigation of co-occurring health conditions across the lifespan for people with Down syndrome. It directs the NIH Director to set research priorities, coordinate activities with stakeholders, and submit a report to Congress every two years cataloging the research supported under the program.

The new provision is added to the Public Health Service Act and focuses on improving and organizing federal research and training efforts about Down syndrome rather than directly changing funding levels or imposing requirements on states or health systems.