Requires new registration, recordkeeping, reporting, serial-numbering, and inspection rules for certain tableting and encapsulating machines and specified "critical parts." Creates a national registry (the National Pill Press Registry), gives the Attorney General authority to define covered machines/parts and to set implementing regulations and fees, and adds new criminal prohibitions and penalties for noncompliance (including removing or possessing machines without required serial numbers). Some provisions take effect within months; others (notably the serial-number ban) are delayed up to two years with narrow compliance/defense windows.