Amends 42 U.S.C. 289d (Section 495 of the Public Health Service Act) by (1) inserting a new subsection (a) that prohibits the National Institutes of Health from awarding any support for activities that use live animals for research unless the research occurs in the United States (defined to include the several States, the District of Columbia, and any U.S. territory or possession); (2) redesignating existing subsections (a) through (e) as (b) through (f); and (3) updating multiple internal cross-references within the section as specified (striking and replacing various subsection citations).