Summary

Creates a class‑wide Schedule I control and legal definition for "fentanyl-related substances," expands criminal‑law coverage, and updates how researchers register and handle Schedule I materials. It directs the Attorney General to publish lists and adopt rules quickly (including interim final rules), changes registration and limited manufacturing procedures for bona fide research, makes clerical fixes to earlier law, and makes most changes effective on enactment.

• Creates a class‑wide Schedule I control and statutory definition for "fentanyl-related substances."
• Gives the Attorney General authority to publish a list of specific fentanyl-related substances in the Federal Register.
• Expedites and streamlines registration for certain Schedule I research, allows single registrations across related sites, and permits limited manufacturing for research use.
• Directs the Attorney General to issue implementing rules within six months and allows interim final rules with comment and hearing opportunities.
• Amends criminal statutes to incorporate the new definition and associated penalty language; effective immediately on enactment.
• Contains clerical cross‑reference corrections to prior statutory text (no substantive policy or funding changes in that part).
• Requires oversight and a 1‑year Inspector General report on implementation of the revised research registration processes.
• Includes a non‑retroactivity/interpretation clause and records congressional agreement with United States v. McCray’s interpretation of the CSA.