Creates a new Joint Task Force to Counter Illicit Synthetic Narcotics (JTF–ISN) to lead, coordinate, and carry out federal efforts against fentanyl and other illicit synthetic drugs. A Senate‑confirmed Director oversees strategy, operations, and regular reports to Congress, including a 2‑year plan and budget priorities.

The task force can coordinate investigations, prosecutions, sanctions, and joint operations with federal, State, territorial, Tribal, and local law enforcement, including actions targeting foreign suppliers and networks linked to the People’s Republic of China. It cannot target people for personal drug use or low‑level dealing that is not connected to larger trafficking networks.