Directs U.S. diplomacy to prioritize the Eastern Mediterranean as a strategic gateway for the India–Middle East–Europe Economic Corridor (IMEC). It urges the United States to lead and participate in multilateral and regional forums, support energy and transportation linkages, deepen defense and security cooperation, and follow existing Eastern Mediterranean policy guidance. The Act also requires the Secretary of State to set up formal strategic dialogues with IMEC partners and deliver reports and briefings to Congress on implementation and options for expanding similar programs.