Requires covered federal agencies to adopt, publish, and obtain Office of Science and Technology Policy (OSTP) approval for formal scientific integrity policies that prohibit suppression or distortion of federally funded research, protect certain speech and petitioning rights, and create agency-level compliance roles and reporting. It sets deadlines for publishing and approving policies, defines prohibited and permitted actions for covered individuals, and establishes OSTP oversight and review duties.

Applies to agencies designated under the America COMPETES Act definition of "covered agency." Existing agency scientific-integrity policies may remain in effect if the agency head submits a written finding and the policy to OSTP for review and approval. The law does not change copyright law and does not appropriate new funds.